Laurence Rustom assists the firm in biotechnology patent prosecution. She has extensive knowledge in the areas of small molecule/antibody/gene/cell therapies, drug formulation, immune checkpoint inhibitors, immuno-modulators, drug delivery vehicles, micro/nanofluidics, biosensors, medical implants.

Prior to joining Wolf Greenfield, she worked as a project manager at Global Prior Art, where she collaborated with client IP attorneys and R&D teams on patent invalidity, patentability, freedom-to-operate and due diligence searches. During graduate school, Laurence designed and conducted in vitro cell culture experiments and two in vivo studies on a pig mandible model to evaluate and enhance bone regeneration in above-critical size bone defects.
  • Society of Women Engineers


  • Rustom, L.E., Poellmann, M.J., Wagoner Johnson, A.J. (2019), Mineralization in micropores of calcium phosphate scaffolds, Acta Biomaterialia, Vol. 83, p.435-455
  • Ho-Shui-Ling A., Bolander, J., Rustom, L.E., Wagoner Johnson, A.J., Luyten, F.P., Picart, C.P. (2018), Bone regeneration strategies: engineered scaffolds, bioactive molecules and stem cells. Current stage and future perspectives, Biomaterials, Vol.80, p.143-162
  • Rustom, L.E., Boudou, T., Nemke, B.W., Lu, Y., Hoelzle, D.J., Markel, M.D., Picart, C., Wagoner Johnson, A.J. (2017), Multiscale porosity directs bone regeneration in biphasic calcium phosphate scaffolds, invitedAmerican Chemical Society Biomaterials Science & Engineering, Vol.3, No.11, p. 2768-2778
  • Rustom, L.E., Boudou, T., Lou, S., Pignot-Paintrand, I., Nemke, B.W., Lu, Y., Markel, M.D., Picart, C., Wagoner Johnson, A.J. (2016), Micropore-induced capillarity enhances bone distribution in vivo in biphasic calcium phosphate scaffolds, Acta Biomaterialia, Vol. 44, p.144-154
  • Xie, Y., Rustom, L.E., McDermott, A.M., Boerckel, J.D., Wagoner Johnson, A.J., Alleyne, A.G., Hoelzle, D.J. (2016), Net shape fabrication of calcium phosphate scaffolds with multiple material domains, Biofabrication, 8(1):015005
  • Polak, S.J., Rustom, L.E., Genin, G.M., Talcott, M., Wagoner Johnson, A.J. (2013) A mechanism for effective cellseeding in rigid, microporous substrates, Acta Biomaterialia, Vol.9, No.8, p.7977-7986
  • Issa, R.I., Engebretson, B., Rustom, L.E., McFetridge, P.S., Sikavitsas, V.I. (2011) The effect of cell seeding density on the cellular and mechanical properties of a mechanostimulated tissue-engineered tendon, Tissue Engineering Part A, Vol.17, No.11-12, p.1479-1487

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Laurence Rustom assists the firm in biotechnology patent prosecution. She has extensive knowledge in the areas of small molecule/antibody/gene/cell therapies, drug formulation, immune checkpoint inhibitors, immuno-modulators, drug delivery vehicles, micro/nanofluidics, biosensors, medical implants.

Prior to joining Wolf Greenfield, she worked as a project manager at Global Prior Art, where she collaborated with client IP attorneys and R&D teams on patent invalidity, patentability, freedom-to-operate and due diligence searches. During graduate school, Laurence designed and conducted in vitro cell culture experiments and two in vivo studies on a pig mandible model to evaluate and enhance bone regeneration in above-critical size bone defects.
  • Society of Women Engineers
  • Rustom, L.E., Poellmann, M.J., Wagoner Johnson, A.J. (2019), Mineralization in micropores of calcium phosphate scaffolds, Acta Biomaterialia, Vol. 83, p.435-455
  • Ho-Shui-Ling A., Bolander, J., Rustom, L.E., Wagoner Johnson, A.J., Luyten, F.P., Picart, C.P. (2018), Bone regeneration strategies: engineered scaffolds, bioactive molecules and stem cells. Current stage and future perspectives, Biomaterials, Vol.80, p.143-162
  • Rustom, L.E., Boudou, T., Nemke, B.W., Lu, Y., Hoelzle, D.J., Markel, M.D., Picart, C., Wagoner Johnson, A.J. (2017), Multiscale porosity directs bone regeneration in biphasic calcium phosphate scaffolds, invitedAmerican Chemical Society Biomaterials Science & Engineering, Vol.3, No.11, p. 2768-2778
  • Rustom, L.E., Boudou, T., Lou, S., Pignot-Paintrand, I., Nemke, B.W., Lu, Y., Markel, M.D., Picart, C., Wagoner Johnson, A.J. (2016), Micropore-induced capillarity enhances bone distribution in vivo in biphasic calcium phosphate scaffolds, Acta Biomaterialia, Vol. 44, p.144-154
  • Xie, Y., Rustom, L.E., McDermott, A.M., Boerckel, J.D., Wagoner Johnson, A.J., Alleyne, A.G., Hoelzle, D.J. (2016), Net shape fabrication of calcium phosphate scaffolds with multiple material domains, Biofabrication, 8(1):015005
  • Polak, S.J., Rustom, L.E., Genin, G.M., Talcott, M., Wagoner Johnson, A.J. (2013) A mechanism for effective cellseeding in rigid, microporous substrates, Acta Biomaterialia, Vol.9, No.8, p.7977-7986
  • Issa, R.I., Engebretson, B., Rustom, L.E., McFetridge, P.S., Sikavitsas, V.I. (2011) The effect of cell seeding density on the cellular and mechanical properties of a mechanostimulated tissue-engineered tendon, Tissue Engineering Part A, Vol.17, No.11-12, p.1479-1487