Joseph Bowler assists the firm in patent prosecution in the biotechnology space, primarily in the areas of next-generation sequencing, antisense therapy and recombinant protein technologies. He also has extensive knowledge in the areas of enzymology, protein biochemistry and structural biology.

Prior to joining the firm, Joseph was a graduate research scientist at Florida State University. While there, he investigated the mechanism of small-molecule activation of an enzyme implicated in the pathogenesis of diabetes. He also developed an in vivo screening method that integrated a plasmid-based library with a genetic selection system to identify novel therapeutic compounds. Joseph’s doctoral work resulted in several publications in research journals, including Nature Chemistry and Proceedings of the National Academy of Sciences.
  • Boston Patent Law Association
  • Joseph M. Schor Fellowship in Biochemistry, Florida State University
  • Trustee Academic Scholarship, Suffolk University Law School
  • Jurisprudence Award in Professional Responsibility, Suffolk University Law School

Blogs

May 1, 2017

In IPRs, Section 112 Can Play a Critical Role—Even Late in the Game



Scientific Publications

Whittington AC, Larion M, Bowler JM, Ramsey KM, Brüschweiler R, Miller BG. (2015) Dual allosteric activation mechanisms in monomeric human glucokinase. Proc Natl Acad Sci USA. 15;112(37):11553-8. 

Bowler JM, Hervert KL, Kearley ML, Miller BG. (2013) Small-Molecule Allosteric Activation of Human Glucokinase in the Absence of Glucose. ACS Med Chem Lett. 5;4(7).

Xiao Q, Jackson JJ, Basak A, Bowler JM, Miller BG, Zakarian A. (2013) Enantioselective synthesis of tatanans A-C and reinvestigation of their glucokinase-activating properties. Nat Chem. 5(5):410-6.


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Joseph Bowler assists the firm in patent prosecution in the biotechnology space, primarily in the areas of next-generation sequencing, antisense therapy and recombinant protein technologies. He also has extensive knowledge in the areas of enzymology, protein biochemistry and structural biology.

Prior to joining the firm, Joseph was a graduate research scientist at Florida State University. While there, he investigated the mechanism of small-molecule activation of an enzyme implicated in the pathogenesis of diabetes. He also developed an in vivo screening method that integrated a plasmid-based library with a genetic selection system to identify novel therapeutic compounds. Joseph’s doctoral work resulted in several publications in research journals, including Nature Chemistry and Proceedings of the National Academy of Sciences.
  • Boston Patent Law Association
  • Joseph M. Schor Fellowship in Biochemistry, Florida State University
  • Trustee Academic Scholarship, Suffolk University Law School
  • Jurisprudence Award in Professional Responsibility, Suffolk University Law School

Scientific Publications

Whittington AC, Larion M, Bowler JM, Ramsey KM, Brüschweiler R, Miller BG. (2015) Dual allosteric activation mechanisms in monomeric human glucokinase. Proc Natl Acad Sci USA. 15;112(37):11553-8. 

Bowler JM, Hervert KL, Kearley ML, Miller BG. (2013) Small-Molecule Allosteric Activation of Human Glucokinase in the Absence of Glucose. ACS Med Chem Lett. 5;4(7).

Xiao Q, Jackson JJ, Basak A, Bowler JM, Miller BG, Zakarian A. (2013) Enantioselective synthesis of tatanans A-C and reinvestigation of their glucokinase-activating properties. Nat Chem. 5(5):410-6.

Blogs

May 1, 2017

In IPRs, Section 112 Can Play a Critical Role—Even Late in the Game