Joseph Bowler assists the firm in biotechnology patent prosecution. He has extensive knowledge in the areas of biochemistry, molecular and cellular biology, and medicinal chemistry.

Prior to joining Wolf Greenfield, Joseph was a graduate research scientist at Florida State University. While there, he investigated the mechanism of action of small-molecule drugs used to treat type 2 diabetes and integrated an in vivo library screening methodology with a genetic selection system to identify novel therapeutic compounds. Joseph was also a graduate teaching assistant at Florida State, where he taught laboratory and lecture courses to undergraduate students.

Joseph’s graduate work resulted in several publications in research journals, including Nature Chemistry and Proceedings of the National Academy of Sciences.

• American Chemical Society

• Joseph M. Schor Fellowship in Biochemistry, Florida State University

Blogs

May 1, 2017

In IPRs, Section 112 Can Play a Critical Role—Even Late in the Game

Scientific Publications

Whittington AC, Larion M, Bowler JM, Ramsey KM, Brüschweiler R, Miller BG. (2015) Dual allosteric activation mechanisms in monomeric human glucokinase. Proc Natl Acad Sci USA. 15;112(37):11553-8. 

Bowler JM, Hervert KL, Kearley ML, Miller BG. (2013) Small-Molecule Allosteric Activation of Human Glucokinase in the Absence of Glucose. ACS Med Chem Lett. 5;4(7).

Xiao Q, Jackson JJ, Basak A, Bowler JM, Miller BG, Zakarian A. (2013) Enantioselective synthesis of tatanans A-C and reinvestigation of their glucokinase-activating properties. Nat Chem. 5(5):410-6.