Allison Brill assists the firm in biotechnology patent prosecution. Allison has extensive knowledge in the areas of cell biology, molecular metabolism, pathology, physiology, pharmacology, and diabetes.

Prior to joining Wolf Greenfield, Allison earned her PhD from Yale University’s Department of Cellular & Molecular Physiology. Her research focused on the Polycystin 2 regulation of mitophagy in non-alcoholic fatty liver disease as well as calcium-mediated mitochondrial dysfunction in kidney disease.
  • NIDDK F31 National Research Service Award Individual Predoctoral Fellowship
  • Molecular Endocrinology Award for Outstanding Publication of 2016


Carpio, M.A.*, Means, R.E.*, Brill, A.L., Sainz, A., Ehrlich, B.E., and Katz, S.G. (2021). “BOK controls apoptosis by calcium transfer through ER- mitochondrial contact sites.” Cell Rep. 34(10):108827.

Schaid, M.D., Green, C.L., Peter, D., Gallagher, S., Guthery, E.E., Carbajal, K.A., Harrington, J.M., Kelly, G.M., Reuter, A.J., Wehner, M.L., Brill, A.L., Neuman, J.C., Lamming, D.W., and Kimple, M.E. (2021). “Agonist-independent Gαz activity negatively regulates β-cell compensation in a diet-induced obesity model of type 2 diabetes.” J Biol Chem. 296:100056.

Truchan, N.A., Fenske, F.J., Sandhu, H.K., Weeks, A.M., Patibandla, C., Wancewicz, B., Pabich, S., Reuter, A., Harrington, J.M., Brill, A.L., Peter, D.C., Nall, R., Daniels, M., Punt, M., Kaiser, C.E., Cox, E.D., Ge, Y., Davis, D.B.*, and Kimple, M.E.* (2021). “Human islet expression levels of Prostaglandin E2 synthetic enzymes, but not Prostaglandin EP3 Receptor, are positively correlated with markers of b-cell function and mass in nondiabetic obesity.” ACS Pharmacology & Translational Science. 4 (4), 1338-1348.

Brill, A. L., Fischer, T.T., Walters, J.M., Marlier, A., Sewanan, L.R., Robert, M.E., Wilson, P.C., Chung, H.J., Campbell, S.G., Cantley, L.G., and Ehrlich, B.E. (2020). "Polycystin 2 is increased in disease to protect against stress-induced cell death." Sci Rep. 10(1): 386.

Perry, R.J., Zhang, D., Guerra, M.T., Brill, A.L., Goedeke, L., Nasiri, A.R., Rabin-Court, A., Wang, Y., Peng, L., Dufour, S., Zhang, Y., Zhang, X.M., Butrico, G.M., Toussaint, K., Nozaki, Y., Cline, G.W., Petersen, K.F., Nathanson, M.H., Ehrlich, B.E., and Shulman, G.I. (2020). “Glucagon stimulates gluconeogenesis by InsP3R-I mediated hepatic lipolysis.” Nature 579(7798): 279-283.

Grosshans, H.K., Fischer, T.T., Steinle, J.A., Brill, A.L., and Ehrlich, B.E. (2020). “Neuronal Calcium Sensor 1 is up-regulated in response to stress to promote cell survival and motility in cancer cells.” Mol Oncol. doi: 10.1002/1878-0261.12678.

Ng, R., Sewanan, L.R., Brill, A.L., Stankey, P., Li, X., Qyang, Y., Ehrlich, B.E., and Campbell, S.G. (2020). "Contractile work directly modulates mitochondrial protein levels in human engineered heart tissues." American journal of physiology. Heart and circulatory physiology 318(6): H1516-h1524.

Brill, A.L.*, Kuo, I.Y*., Lemos, F.O., Jiang, J.Y., Falcone, J.L., Kimmerling, E.P., Cai, Y., Dong, K., Kaplan, D.L., Wallace, D.P., Hofer, A.M., and Ehrlich, B.E. (2019). “Polycystin 2 regulates mitochondrial calcium signaling, bioenergetics, and dynamics through mitofusin 2.” Sci Signaling. 12, eaat7397.

Neuman, J.C., Schaid, M.D., Brill, A.L., Fenske, R.J., Kibbe, C.R., Fontaine, D.A., Sdao, S.M., Brar, H.K., Connors, K.M., Wienkes, H.N., Eliceiri, K.W., Merrins, M.J., Davis, D.B., and Kimple, M.E. (2017). “Enriching Islet Phospholipids with Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic b-Cell Function.” Diabetes. 66(6):1572-1585.

Fenske, R.J., Cadena, M.T., Harenda, Q.E., Wienkes, H.N., Carbajal, K., Schaid, M.D., Laundre, E., Brill, A.L., Truchan, N.A., Brar, H.K., Wisinski, J.A., Jinjin, C., Graham, T.E., Engin, F., and Kimple, M.E. (2017). “The Inhibitory G-protein α-subunit, Gαz, promotes Type 1 diabetes-like pathophysiology in NOD mice.” Endocrinology. 158(6):1645-1658.

Brill, A.L., Wisinski, J.A., Cadena, M.T., Thompson, M.F., Fenske, R.J., Brar, H.K., Schaid, M.D., Pasker, R.L., and Kimple, M.E. (2016). “Synergy Between Gαz Deficiency and GLP-1 Analog Treatment in Preserving Functional b-Cell Mass in Experimental Diabetes.” Mol Endocrinol. 30(5):543-556.

Pierre, J.F.*, Neuman, J.C.*, Brill, A.L., Brar, H.K., Thompson, M.F., Cadena, M.T., Connors, K.M., Busch, R.A., Heneghan, A.F., Cham, C.M., Jones, E.K., Groblewski, G.E., Chang, E.B., and Kudsk, K.A., Kimple, M.E. (2015). “The Gastrin Releasing Peptide Analog, Bombesin, Preserves the Exocrine Pancreas and Enteroendocrine Cell-Pancreas Axis during Parenteral Nutrition.” Am J Physiol: Gastrointest. Liver Physiol. 309(6):G431-442.

Tennis, baking, travel, and finding fun spots to eat new foods!

Expand All
Allison Brill assists the firm in biotechnology patent prosecution. Allison has extensive knowledge in the areas of cell biology, molecular metabolism, pathology, physiology, pharmacology, and diabetes.

Prior to joining Wolf Greenfield, Allison earned her PhD from Yale University’s Department of Cellular & Molecular Physiology. Her research focused on the Polycystin 2 regulation of mitophagy in non-alcoholic fatty liver disease as well as calcium-mediated mitochondrial dysfunction in kidney disease.
  • NIDDK F31 National Research Service Award Individual Predoctoral Fellowship
  • Molecular Endocrinology Award for Outstanding Publication of 2016
Carpio, M.A.*, Means, R.E.*, Brill, A.L., Sainz, A., Ehrlich, B.E., and Katz, S.G. (2021). “BOK controls apoptosis by calcium transfer through ER- mitochondrial contact sites.” Cell Rep. 34(10):108827.

Schaid, M.D., Green, C.L., Peter, D., Gallagher, S., Guthery, E.E., Carbajal, K.A., Harrington, J.M., Kelly, G.M., Reuter, A.J., Wehner, M.L., Brill, A.L., Neuman, J.C., Lamming, D.W., and Kimple, M.E. (2021). “Agonist-independent Gαz activity negatively regulates β-cell compensation in a diet-induced obesity model of type 2 diabetes.” J Biol Chem. 296:100056.

Truchan, N.A., Fenske, F.J., Sandhu, H.K., Weeks, A.M., Patibandla, C., Wancewicz, B., Pabich, S., Reuter, A., Harrington, J.M., Brill, A.L., Peter, D.C., Nall, R., Daniels, M., Punt, M., Kaiser, C.E., Cox, E.D., Ge, Y., Davis, D.B.*, and Kimple, M.E.* (2021). “Human islet expression levels of Prostaglandin E2 synthetic enzymes, but not Prostaglandin EP3 Receptor, are positively correlated with markers of b-cell function and mass in nondiabetic obesity.” ACS Pharmacology & Translational Science. 4 (4), 1338-1348.

Brill, A. L., Fischer, T.T., Walters, J.M., Marlier, A., Sewanan, L.R., Robert, M.E., Wilson, P.C., Chung, H.J., Campbell, S.G., Cantley, L.G., and Ehrlich, B.E. (2020). "Polycystin 2 is increased in disease to protect against stress-induced cell death." Sci Rep. 10(1): 386.

Perry, R.J., Zhang, D., Guerra, M.T., Brill, A.L., Goedeke, L., Nasiri, A.R., Rabin-Court, A., Wang, Y., Peng, L., Dufour, S., Zhang, Y., Zhang, X.M., Butrico, G.M., Toussaint, K., Nozaki, Y., Cline, G.W., Petersen, K.F., Nathanson, M.H., Ehrlich, B.E., and Shulman, G.I. (2020). “Glucagon stimulates gluconeogenesis by InsP3R-I mediated hepatic lipolysis.” Nature 579(7798): 279-283.

Grosshans, H.K., Fischer, T.T., Steinle, J.A., Brill, A.L., and Ehrlich, B.E. (2020). “Neuronal Calcium Sensor 1 is up-regulated in response to stress to promote cell survival and motility in cancer cells.” Mol Oncol. doi: 10.1002/1878-0261.12678.

Ng, R., Sewanan, L.R., Brill, A.L., Stankey, P., Li, X., Qyang, Y., Ehrlich, B.E., and Campbell, S.G. (2020). "Contractile work directly modulates mitochondrial protein levels in human engineered heart tissues." American journal of physiology. Heart and circulatory physiology 318(6): H1516-h1524.

Brill, A.L.*, Kuo, I.Y*., Lemos, F.O., Jiang, J.Y., Falcone, J.L., Kimmerling, E.P., Cai, Y., Dong, K., Kaplan, D.L., Wallace, D.P., Hofer, A.M., and Ehrlich, B.E. (2019). “Polycystin 2 regulates mitochondrial calcium signaling, bioenergetics, and dynamics through mitofusin 2.” Sci Signaling. 12, eaat7397.

Neuman, J.C., Schaid, M.D., Brill, A.L., Fenske, R.J., Kibbe, C.R., Fontaine, D.A., Sdao, S.M., Brar, H.K., Connors, K.M., Wienkes, H.N., Eliceiri, K.W., Merrins, M.J., Davis, D.B., and Kimple, M.E. (2017). “Enriching Islet Phospholipids with Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic b-Cell Function.” Diabetes. 66(6):1572-1585.

Fenske, R.J., Cadena, M.T., Harenda, Q.E., Wienkes, H.N., Carbajal, K., Schaid, M.D., Laundre, E., Brill, A.L., Truchan, N.A., Brar, H.K., Wisinski, J.A., Jinjin, C., Graham, T.E., Engin, F., and Kimple, M.E. (2017). “The Inhibitory G-protein α-subunit, Gαz, promotes Type 1 diabetes-like pathophysiology in NOD mice.” Endocrinology. 158(6):1645-1658.

Brill, A.L., Wisinski, J.A., Cadena, M.T., Thompson, M.F., Fenske, R.J., Brar, H.K., Schaid, M.D., Pasker, R.L., and Kimple, M.E. (2016). “Synergy Between Gαz Deficiency and GLP-1 Analog Treatment in Preserving Functional b-Cell Mass in Experimental Diabetes.” Mol Endocrinol. 30(5):543-556.

Pierre, J.F.*, Neuman, J.C.*, Brill, A.L., Brar, H.K., Thompson, M.F., Cadena, M.T., Connors, K.M., Busch, R.A., Heneghan, A.F., Cham, C.M., Jones, E.K., Groblewski, G.E., Chang, E.B., and Kudsk, K.A., Kimple, M.E. (2015). “The Gastrin Releasing Peptide Analog, Bombesin, Preserves the Exocrine Pancreas and Enteroendocrine Cell-Pancreas Axis during Parenteral Nutrition.” Am J Physiol: Gastrointest. Liver Physiol. 309(6):G431-442.


Tennis, baking, travel, and finding fun spots to eat new foods!